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azacytidine receptor A range of therapies exists for the
2021-02-19

A range of therapies exists for the treatment of inflammation-driven diseases, which can be summarized as non-steroidal anti-inflammatory drugs (NSAIDs), corticoids and steroidal-related drugs (Ward et al., 2008). Despite of these notable successes, there are still major unmet medical needs in the t
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Our results also showed that the highest dose
2021-02-19

Our results also showed that the highest dose of Astressin2-B increased the rewarding effects of cocaine, since non-defeated animals treated with this dose developed CPP with a sub-threshold dose. We monitored the acute effects of 30 µg/kg of Astressin2-B and found an increase of anxiety in the open
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Completion of h of education was significant in virtually
2021-02-19

Completion of 150 h of education was significant in virtually all prior studies of the 150-h requirement (Allen and Woodland, 2006, Boone et al., 2006 and others). While the 150-h requirement applies to licensure, students are often permitted (as in California) to sit for the CPA exam with fewer tot
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br Discussion EFTs are sarcomas with almost undifferentiated
2021-02-19

Discussion EFTs are sarcomas with almost undifferentiated histologic features, consequently their differentiation from other small, blue, round cell tumors may be difficult. Substantial intracellular Apocynin on PAS stain is a useful diagnostic feature. The addition of CD99 and FLI1 immunohistoc
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br Acknowledgments br Introduction Cholesterol is an essenti
2021-02-19

Acknowledgments Introduction Cholesterol is an essential lipid for the development, growth, and wellbeing of humans. In newborn children, cord blood cholesterol concentration is 1.5 mmol/l, on average [[1], [2], [3], [4]]. During the first year of life, cholesterol concentration in serum incre
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ClC is a member of the
2021-02-19

ClC-3 is a member of the voltage-gated chloride channel superfamily and has many roles in cell proliferation, apoptosis, pimaricin progression and so on (Dai et al., 2005). A growing number of studies showed that ClC-3 encoded a volume-regulated Cl− channel (ICl,Vol) in heart, that could contribute
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Overall we found that all hormone treatment
2021-02-19

Overall, we found that all hormone treatment groups were able to learn spatial working and reference memory tasks, as shown by their performance across days on the WRAM (days 2–12, collapsed across the 4 trials) and the MWM (days 1–5, collapsed across the 4 trials). During the acquisition phase of t
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Many researchers studied the experimental investigation of R
2021-02-19

Many researchers studied the experimental investigation of RHA in cement enhances the strength and durability of the concrete [9], [10], [11], [12]. It is most important that concrete must withstand its strength even after it is being exposed to any corrosive environment over a period of time. In ad
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Introduction Penetrator with Enhanced Lateral Effect PELE is
2021-02-19

Introduction Penetrator with Enhanced Lateral Effect (PELE) is a kind of ammunition which consists of a low-density material as the filling and a high-density material as the jacket [1,2]. When PELE impact target, the jacket is radially accelerated, expanded and fractured because of distinctive lat
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Interestingly anti inflammatory actions for sPLA V
2021-02-19

Interestingly, anti-inflammatory actions for sPLA2-V were also described in mice a few years ago in a model of autoimmune complex mediated arthritis [148]. A novel mechanism was delineated, whereby sPLA2-V promotes phagocytosis of immune complexes by macrophages to ameliorate inflammation in autoimm
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Enolase is an example of a moonlighting
2021-02-18

Enolase is an example of a moonlighting protein that displays multiple biological actions, including plasminogen, laminin, fibronectin, mucin and cytokeratin binding properties. It has also been described as a complement-evasion protein and as a protein capable of inducing neutrophil trap formation.
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CORM-3 mg It was thus found that E plays an
2021-02-18

It was thus found that E1 plays an important role in G. intestinalis biology. Inhibiting E1 expression by RNA antisense in trophozoites was lethal while E1 overexpression induced a five-fold increase in cyst formation during encystation. The changes in E1 location during this process and its localiz
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The differences between ground and transition state properti
2021-02-18

The differences between ground and transition state properties are exemplified by a comparison of our human–yeast results with those of a structural study of possible differences in ubiquitin-Uba-1 binding in yeast (known structure) with human (simulated in [12]). Their discussion focuses on Ubiquit
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Finally the effect of the BMIM
2021-02-16

Finally, the effect of the [BMIM][BF4] concentration change on the P-T diagram of methane hydrate was predicted using the proposed model. Three various concentrations (including 10%, 15% and 20%) were considered for calculations. The experimental data [49] and modeling results are demonstrated and c
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Within their range of applicability
2021-02-16

Within their range of applicability, both approaches matched the phase boundaries and yields generally to within the measurement error. The approaches matched the phase compositions generally to within 11 wt% or less with the average absolute deviations listed below: One advantage of the proposed a
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